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Uveitis: Funda thelium may occasionally spread over the iris and line the mentals and Clinical Practice. The radius of the lens is composed of 64% water, 35% protein, and curvature of the anterior surface of the lens is 10 mm and 1% lipid, carbohydrate and trace elements. The former shortens with centration in the lens is actually the highest amongst body accommodation. The main types of proteins are alpha (31%), beta the function of the lens (like the cornea) is to transmit (55%) and gamma (2%) crystallins, and insoluble albumi and refract light. Lactate produced by and in this respect it is unique among the organs of the the anaerobic metabolism diffuses into the aqueous. At birth its weight is about 65 mg and by 80 years of cortex is the most metabolically active region and the energy age it has been found to weigh 258 mg. The lens capsule is a thick, col nucleus (d) Epinucleus lagenous basement membrane which is transparent, is thickest at the anterior pre equatorial region and thinnest at the posterior pole. The cells are interconnected by gap junctions and ermost and going successively deeper inwards a) capsule, b) peripheral cor desmosomes and not by tight junctions or zona occludens, tex, c) supranuclear cortex, d) epinucleus (outermost nucleus or innermost unlike typical epithelial cells. Ions and metabolites of low cortex), e) adult nucleus, f) fetal nucleus which corresponds to the cotyle molecular weight can be exchanged. The lens epithelium donous areas of light scattering apparent within the clear adult lens and g) secretes the lens capsule and regulates the transport of embryonic nucleus which is the innermost core of nucleus. The lens fbres are produced by the mitosis of epithelial cells in the pre-equatorial zone, which elongate and undergo differentiation with pyknocytosis and eventual loss of cell organelles and the nucleus. As the lens fbres elongate and new A ones form, the older ones are pushed towards the depth of the lens so that the youngest lens fbres are the most super fcially located. Ninety per cent of the mass of the B C lens fbres consists of proteins called crystallins (alpha crystallin, beta-crystallin and gamma-crystallin). The nucleus includes an embryonic marked by the elliptical mask (B), and a digital slit-lamp photograph of the nucleus consisting of primary lens fbres surrounded by the same lens (C). Care, however, nucleus consists of densely compacted lens fbres and has a should be taken in using this term clinically as it often higher refractive index than that of the cortex (Fig 18. This ap the cortex is seen as zones which are alternately dark plies particularly to the stationary types of opacity. It is to and bright on oblique illumination with a slit-lamp, depend be remembered that even in senile cataract the opacities ing on the propensity to scatter light to a lesser or greater may remain localized for years without causing serious dis extent (Fig 18.
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For a list of examples of human chemical carcinogens, and the relevant target organs, refer to Table 5. Cristobalite A crystalline form of free silica, extremely hard and inert chemically; very resistant to heat. Quartz in refractory bricks and amorphous silica in diatomaceous earth are altered to cristobalite when exposed to high temperatures (calcined). Cristobalite is extensively used in precision casting by the hot wax process, dental laboratory work, and certain speciality ceramics. Flint A microcrystalline form of native quartz, more opaque and granular than chalcedony. Quartz Vitreous, hard, chemically-resistant free silica, the most common form in nature. Tripoli (rottenstone) A porous siliceous rock resulting from the decomposition of chert or siliceous limestone. Used as a base in soap and scouring powders, in metal polishing, as a filtering agent, and in wood and paint fillers. Amorphous free silica (Noncrystalline) Diatomaceous earth A soft, gritty amorphous silica composed of minute siliceous skeletons of small aquatic plants. Used in filtration and decoloration of liquids, insulation, filler in dynamite, wax, textiles, plastics, paint, and rubber. Calcined and flux-calcined diatomaceous earth contains appreciable amounts of cristobalite, and dust levels should be the same as for cristobalite. Silicates (compounds made up of silicon, oxygen and one or more metals with or without hydrogen. Feldspar Most abundant group of materials, composed of silicates of aluminium with sodium, potassium, calcium, and rarely barium. Used as a filter medium and as a catalyst and catalyst carrier and in cosmetics and insecticides. Kaolin A type of clay composed of mixed silicates and used for refractories, ceramics, tile and stoneware. Mica A large group of silicates of varying composition, but similar in physical properties. Portland cement Fine powder containing compounds of lime, alumina, silica and iron oxide. Talc A hydrous magnesium silicate used in ceramics, cosmetics, paint and pharmaceuticals, and as a filler in soap, putty and plaster. Used in lightweight aggregates, insulation, fertilizer and soil conditioners, as a filler in rubber and paints, and as a catalyst carrier. It is therefore an indicator of acute toxicity, usually determined by ingestion using rats or mice, although other animals may be used.
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Those midlife adults who have a strong sense of mastery and control over their lives, who engage in challenging physical and mental activity, who engage in weight bearing exercise, monitor their nutrition, receive adequate sleep, and make use of social resources are most likely to enjoy a plateau of good health through these years (Lachman, 2004). Climacteric the climacteric, or the midlife transition when fertility declines, is biologically based but impacted by the environment. The average age of menopause is approximately 51, however, many women begin experiencing symptoms in their 40s. These symptoms occur during perimenopause, which can occur 2 to 8 years before menopause (Huang, 2007). A woman may first begin to notice that her periods are more or less frequent than before. After a year without menstruation, a woman is considered menopausal and no longer capable of reproduction. Symptoms: the symptoms that occur during perimenopause and menopause are typically caused by the decreased production of estrogen and progesterone (North American Menopause Society, 2016). Additionally, the declining levels of estrogen may make a woman more susceptible to environmental factors and stressors which disrupt sleep. It often produces sweat and a change of temperature that can be disruptive to sleep and comfort levels. Unfortunately, it may take time for adrenaline to recede and allow sleep to occur again (National Sleep Foundation, 2016). The loss of estrogen also affects vaginal lubrication which diminishes and becomes waterier and can contribute to pain during intercourse. Estrogen is also important for bone formation and growth, and decreased estrogen can cause osteoporosis resulting in decreased bone mass. Depression, irritability, and weight gain are often associated with menopause, but they are not menopausal (Avis, Stellato & Crawford, 2001; Rossi, 2004). Weight gain can occur due to an increase in intra-abdominal fat followed by a loss of lean body mass after menopause (Morita et al. Depression and mood swings are more common during menopause in women who have prior histories of these conditions rather than those who have not. Additionally, the incidence of depression and mood swings is not greater among menopausal women than non-menopausal women. Hormone Replacement Therapy: Concerns about the effects of hormone replacement has changed the frequency with which estrogen replacement and hormone replacement therapies have been prescribed for menopausal women. Most women do not have symptoms severe enough to warrant estrogen or hormone replacement therapy. If so, they can be treated with lower doses of estrogen and monitored with more frequent breast and pelvic exams. These include avoiding caffeine and alcohol, eating soy, remaining sexually active, practicing relaxation techniques, and using water-based lubricants during intercourse.
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While dry eye can affect people at any age, nearly 5 million Americans over the age of 50 experience dry eye. Women who experienced an early menopause may be more likely to experience dry eye, which can cause surface damage to the eye. This jumps to 19% among 40 to 69 year-olds 10 (American Psychological Association, 5 2016). Middle-aged adults may experience 0 more problems understanding speech when 40-44 45-49 50-54 55-59 60-64 65-69 in noisy environments, in comparison to younger adults (Fullgrabe, Moore, & Stone, Adapted from Dawes, et al. As we age we also lose the ability to hear higher frequencies (Humes, Kewley-Port, Fogerty, & Kinney, 2010). Hearing changes are more common among men than women, but males may underestimate their hearing problems (Uchida, Nakashima, Ando, Niino, & Shimokata, 2003). For many adults, hearing loss accumulates after years of being exposed to intense noise levels. Hearing loss is also exacerbated by cigarette smoking, high blood pressure, diabetes, and stroke. Most hearing loss could be prevented by guarding against being exposed to extremely noisy environments. It is also the number one cause of death worldwide (World Health Organization, 2018). Heart disease develops slowly over time and typically appears in midlife (Hooker & Pressman, 2016). Heart disease can include heart defects and heart rhythm problems, as well as narrowed, blocked, or stiffened blood vessels referred to as cardiovascular disease. The blocked blood vessels prevent the body and heart from receiving adequate blood. Atherosclerosis, or a buildup of fatty plaque in the arteries, is the most common cause of cardiovascular disease. The plaque buildup thickens the artery walls and restricts the blood flow to organs and tissues. Cardiovascular disease can lead to a heart attack, chest pain (angina), or stroke (Mayo Clinic, 2014a). Males are more likely to suffer chest pain, while women are more likely to demonstrate shortness of breath, nausea, and extreme fatigue. Symptoms can also include pain in the arms, legs, neck, jaw, throat, abdomen or back (Mayo Clinic, 2014a). According to the Mayo Clinic (2014a) there are many risk factors for developing heart disease, including medical conditions, such as high blood pressure, high cholesterol, diabetes, and obesity.