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The demanding environment of space in which all spacecraft are asked to operate in, brings with it exposure to several extreme factors, namely radiation. Stepper motor and multi-stage planetary transmission (A), idler gear shaft (B), output shaft and gear (C), and cable wrap (D). Semiconductor based electronic components are inherently susceptible to unwanted effects of space radiation. The first class, cumulative effects are brought on gradually throughout the lifetime of exposure in a radiation rich environment. The upper limit on the cumulative amount of radiation a susceptible component can accept before failure is referred to as the total ionizing dose. Total ionizing dose is the measure of the cumulative dose of energy transferred into the material by radiation in the form of ionizing energy. Thorough testing and characterization of a component can be used to confidently assess its total ionizing dose. The second class, single event effects are quite different in that they can be attributed to the energy transferred by a single particle interacting with an electronic device. Single event upsets typically appear as transient signals, or as bit changes in memory stores. In contrast to single event upsets, which are only seen in software, there exists a counterpart in hardware, single event latch-up. Single event latch-ups can result in higher operating currents which can lead to component degradation and possible failure. Traditionally space systems have been designed using a limited number of electronic components, whose limited variety can be attributed to availability of their radiation hardened versions. However, a migration from traditional rad hard components is currently underway, thanks to the commercialization of space. Consequently, space manufacturers around the world are faced with a requirement to build satellites that are faster, better and cheaper than those made in the iv past. Other techniques such as hot-redundancy are also employed in the case of memory access.
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Because of its rapidly progressive, aqueous outflow and elevate intraocular pressure, pro potentially devastating course, infectious endopthalmitis ducing lens particle glaucoma. Lens particle glaucoma is gen sent following ocular surgery or trauma with elevated erally more subacute and the presence of visible lens intraocular pressure and uveitis, often with visible cortical material is key to the correct diagnosis. A history of prior uveitis, or of signs and symptoms consistent with systemic disease associated with Despite the increasing popularity of extracapsular cataract uveitis, may help differentiate other uveitic glaucomas techniques, lens particle glaucoma remains relatively from lens particle glaucoma. This may be due to improved methods and glaucoma following trauma should be examined carefully instrumentation for removing lens cortex. Patients with open-angle glaucoma tolerate retained cortical material more poorly Symptoms Onset following ocular surgery or trauma than patients with a healthy outflow mechanism. This requires aqueous sup synechiae, or angle closure from peripheral anterior pressants, such as beta-blockers, alpha agonists, carbonic synechiae. This is almost always a retrospective, histopatho anhydrase inhibitors, and occasionally, hyperosmotic logic diagnosis, and treatment requires removal of the incit agents27 in addition to topical and, if necessary, oral corti ing lens material. Cycloplegics often improve comfort and can prevent the formation of posterior synechiae. If these measures fail, Phacoanaphylactic endophthalmitis was first recognized surgical removal of all lens debris is indicated to prevent in 1919, and Verhoeff and Lemoine defined the condition their entrapment in inflammatory membranes, permanent in 1922. Although some investigators theorize surgery that this reaction represents an immune rejection of sequestered, foreign lens material, others have suggested P. A hypopyon may recur as the inflammation waxes and wanes in response to treatment. Definitive diagnosis relies on the histopathologic demonstration of a typical, zonal granulomatous response. Low-power photomicrograph of a periodic acid-Schiff stained specimen, coanaphylactic glaucoma. Gram stain and culture of a showing disrupted capsule (arrow) and lens material (L) diagnostic anterior chamber or vitreous tap can help surrounded by zonal inflammation (Z). These forms of glaucoma can be differentiated by histologic to the loss of the normal tolerance to lens proteins. Recent manu Although firmly entrenched in the literature, the term facturing improvements have markedly improved ocular phacoanaphylaxis is misleading because this does not tolerance to intraocular lenses. Other potential open-angle mechanisms include direct inflammation of the trabecular meshwork and Initial management is directed toward controlling steroid-induced elevation in intraocular pressure. Unfortunately, although top ical, subconjunctival, and even systemic corticosteroids37 closure glaucoma can result from the development of peripheral anterior synechiae and pupillary block from may produce an initial improvement in the uveitis, this extensive posterior synechiae. Steroid response of the intraocular pressure the reported incidence of all forms of persistent, post in susceptible patients may further complicate glaucoma operative uveitis, from which phacoanaphylactic treatment.
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The study found that a greater proportion of those who Both publications (H oving et al. The methodological limita in pain at seven weeks compared with 39% for those treated tions of the study were noted in another systematic review with physical therapy and 30% for those under usual care. At four weeks and eight Reductions in disability amounted to 30% and were not signif weeks after treatment, the mobilisation and exercise group icantly different between groups. Improvements in quality of exhibited a significantly greater reduction of pain, from a mean life measures were significantly better for the manual therapy score at baseline of 5. For the group and amounted to 22% for manual therapy, 12% for control group the corresponding figures were 6. Even so, there was consider For relief of pain, the effect size for manual therapy was able variance in the outcomes of the index treatment group. For improvement in quality of life, diathermy, hydrotherapy, active and passive movements, trac the effect size for manual therapy was not much higher than tion, advice on posture and home exercises) tailored to indi that of physical therapy (0. Overall, these results indicated that and the effects of instruction to perform mobilisation exercises manual therapy was moderately more effective than usual care at home and postural education. Tailored multi-modal therapy and marginally more effective than physical therapy (Hoving et was not more effective than home exercises, but both interven al. They reported this study is the only one that has provided long-term that 68% of their patients treated with manual therapy had follow-up (M cKinney 1989). At two years, 77% of the home recovered at seven weeks compared with 51% of patients exercise group were pain-free compared with 56% in the treated by physical therapy and 36% of patients under usual outpatient group and 54% in the rest and analgesia group. In these terms, there was substantially greater than that of the tailored package of fore, manual therapy is substantially more favourable than outpatient treatments (1. This could be an important factor in light of the fact Pulsed electrom agnetic therapy reduces pain intensity com pared to that those treated with manual therapy averaged six visits, placebo in the short term but is no different to placebo at 12 weeks for whereas those under usual care averaged only two visits. The thesis (Hoving 2001), however, the literature on acupuncture for neck pain is limited to reveals that any difference in outcome diminishes with time. At studies involving chronic pain, mixed acute and chronic pain 13 weeks, a significantly higher proportion (72%) of people or specific conditions causing pain. It provides insufficient who had manual therapy felt they had recovered compared evidence concerning the management of acute neck pain. Neither of these proportions was Exploring the literature on mixed populations does not different from that of the physical therapy group (59%). Clinical Evidence (2002) cited two systematic reviews (W hite and Ernst 1999; Smith et al.
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