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By: B. Sanuyem, M.A., M.D., M.P.H.
Co-Director, University of California, Irvine School of Medicine
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Protection of U937 cells against oxidative injury by a novel series of iron chelators. Protective effects of dehydroepiandrosterone against lipid peroxidation in human liver cell line. Analysis of phenolic and flavonoid compounds in juice beverages using high performance liquid chromatography with coulometric array detection. Redox cycling and sulfhydryl arylation: Their relative importance in the mechanism of quinone cytotoxicity to isolated hepatocytes. Apomorphine, a dopamine receptor agonist with remarkable antioxidant and cytoprotective properties. Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor. A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. A critical and constructive review of epidemiology and supplementation data regarding cardiovascular disease and cancer. Inverse correlation between vitamin E and mortality from ischemic heart disease in cross cultural epidemiology. Electrochemical and in vitro evaluation of the redox properties of kynurenine species. Pro oxidant and antioxidant effects of ascorbate on photosensitized peroxidation of lipids in erythrocyte membranes. Melatonin protects primary cultures of cerebella granule neurons from kainate but not from N methyl D aspartate excitotoxicity. Tear fluid content of electrochemically active components including water soluble antioxidants. Determination of melatonin by high performance liquid chromatography with electrochemical detection. Estrogens attenuate and corticosterone exacerbates excitoxicity, oxidative injury, and amyloid peptide toxicity in hippocampal neurons. Simultaneous determination of retinyl esters and retinol in human livers by reversed phase high performance liquid chromatography. Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones. Differential protein S thiolation of glyceraldehyde 3 phosphate dehydrogenase isoenzymes influences sensitivity to oxidative stress. The efficacy of monohydroxamates as free radical scavenging agents compared to di and tri hydroxymates.
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Ossifcation of the external Conclusion ear: a case report and review of the literature. Eur Arch langes), peripheral pulmonary artery ste Otorhinolaryngol 2005, 262: 961 964. Gonzalez Sixton B, Garcia Doval I, Conde A, Mayo E, nosis, hearing loss, dysmorphic facies, and the petrified auricle is an uncommonly Pardavila R, de la Torre C, et al. Secondary ectopic ossification of the the often asymptomatic nature of this con 36. Auricular ossifcation resulting in Neoplasms associated with ossification external auditory canal stenosis. Cli Recessive Syndrome: Peripheral Pulmonary Stenosis, of Nanta, pilomatrixoma, and chondroid nicians are encouraged to examine the pin Brachytelephalangism, Neural Hearing Loss, and Abnormal syringoma. A Slowly Progressive Degenerative Condition inflammation, repetitive trauma, and idio Characterized by Mental Defciency, Wasting of Limb discovery of an undiagnosed systemic condi Musculature and Bone Abnormalities, Including Ossifcation pathic. Ossifcation of the Auricles: associated with auricular ossification is A Forgotten Sign in Adrenal Insuffciency. Verknocherung der Ohrmuschel und curled his prominent pinna and inserted it Roentgenographie. Calcigerous Metaplasia of the Auricular manipulation is referred to as acrobatic Cartilage. Auricular ossifcans (ectopic insult that leads to a cascade of mediators ossifcation of the auricle). Petrifed ears: Calcifcation frostbite as an etiology, this type of hypo of the auricular cartilage. Pinnal calcifcation: genetic protein, which acts upon the mes observations in systemic diseases not associated with disordered calcium metabolism. Calcifcation of the auricular Treatment of auricular ossificans is not cartilage in a patient with hypopituitarism. J Clin Endocrinol Metab 18 BiLateraL idiopathiC auriCuLar ossiFiCans: a Case report and reView oF the Literature Figure 3. The right auricle appears nor cle demonstrates parallel densities in the Figure 1. The left auricle appears nor mal but moves as a solid, fixed unit with shape of the auricular cartilage consistent mal but moves as a unit and does not pressure from a cotton tipped applicator. A scar is notable in the scaphoid fossa from resection of the squamous cell carcinoma by Mohs micro graphic surgery. High power (40X) view of the biopsy from the left auricle demonstrates biopsy from the left auricle demonstrates trabecular bone formation.
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Corresponding author: Stephanie Cox, Department of Endocrinology, Waikato Hospital, Private Bag 3200 Hamilton, 3420, New Zealand. Gimm O, Brauckhoff M, Europe, Japan, and the Zealand: incidence and Thanh P, Sekulla C, Dralle United States. Increased Lagasse R, Nagayama and management of cancer incidence after Y, Izumi M. Differences Graves disease: a global radioiodine treatment and similarities in the overview. Torring O, Tallstedt L, management, and compli Management of Thyroid Wallin G et al. Response risks from computed new zealand becomes nu rates in postal surveys of tomographic scans clear free, (Ministry for healthcare profession performed in the United Culture and Heritage), als between 1995 and States in 2007. We calculated prevalence estimates and 95% confidence intervals and used binary logistic regression to map geographical variations in diabetes. Such variations remained afer binary logistic regression adjusting for socio demographic variables. Compared to New Zealand Europeans, Indian people had the highest odds of having diabetes at 3. These inequities should prompt action by politicians, policymakers, funders, health providers and communities for interventions aimed at reducing such inequities. Geography and its implications on access to and availability of health resources appears to be a key driver of inequity in diabetes rates, supporting an argument for interventions based on geography, especially a public health rather than an individual risk approach. They were also identifed deprived quintile having a diabetes preva from the following classes of dispensed lence of 4. Population age tions were seen in those aged 70 to 74 and and gender specifc denominators were 75 to 79 years (both 15. A customisable online Pacifc, or Other ethnic groupings, and version of this data with the accompanying the Other Ethnic group was used as the maps is available to access from view. The highest diabetes prevalence was value to lowest values and its interpretation 17. The west Auckland areas diabetes, controlling for their age, gender, of Waitakere, The Atatu and New Lynn had ethnicity and neighbourhood deprivation intermediate levels of diabetes. Therefore the rates for these groups may difer slightly from the (unadjusted) rates reported in Table 1.
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Severe hypercholesterolemia: automated dextran sulfate cellulose adsorption system. Familial hypercholesterol tein apheresis using an automated dextran sulfate cellulose adsorption emia regression study: a randomized trial of low density lipoprotein system. Other causes include mutations in specific podocyte genes, secondary to drugs, and hemodynamic adaptive response. The successful use of immunoadsorption techniques with various ligands demonstrates that putative circulating factors have immunoglobulin like binding characteristics. Despite treatment, 30 60% of patients progress to end stage renal disease within 3 7 years. Other risk factors for recurrence are younger age, short duration of native kid ney disease, history of recurrence with previous transplant, heavy proteinuria, bilateral native nephrectomy, race, and living donor kidney. Delayed treatment initition (>2 weeks) appears to be more common in non responders. Studies support the need for immunosuppression as well as continuing therapeutic apheresis. Technical notes In addition to peripheral or central lines, vascular access may be obtained through arteriovenous fistulas or grafts used for dialysis. Tapering of apheresis treatment should be decided on a case by case basis and is guided by the degree of proteinuria. Timing of clinical response is variable and complete abolishment of proteinuria may take several weeks to months. The role of plasma exchange in treating post transplant focal segmental glomerulosclerosis: a systematic review and meta analysis of 77 case reports and case series. Long term efficacy of low peutic plasma exchange forarticlespublishedintheEnglish language. Rituximab and therapeutic immunoadsorption for the recurrence of idiopathic focal segmental plasma exchange in recurrent focal segmental glomerulosclerosis glomerulosclerosis in the graft: a single center experience. Treatment by immunoadsorption for recur Moroni G, Gallelli B, Quaglini S, Banfi G, Montagnino G, Messa P. Long rent focal segmental glomerulosclerosis after pediatric kidney transplan term outcome of renal transplantation in adults with focal segmental tation: a multicentre French cohort. Recurrent primary focal segmental plasmapheresis and immunoadsorption should be associated with better glomerulosclerosis managed with intensified plasma exchange and con prognosis. Importantly, steroid sparing effect occurs, even in absence of organ improvement, and therefore improves quality of life. Two treatments (typi cally on consecutive days) in 1 week are often designated 1 cycle. Successful use of mini photopheresis for the treatment of graft versus host disease. The role of extracorporeal photo disease after allogeneic marrow transplantation: clinical practice guidelines pheresis in the management of cutaneous T cell lymphoma, graft versus based on field experience andreviewoftheliterature.
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